Observations on the Use of Nicotinic Acid in the Treatment of Pellagra and Allied Conditions
نویسنده
چکیده
In September 1937 Elvehjem et al. discovered that a single dose of 30 nig. of Eastman Kodak Company nicotinic acid improved the appetite and stopped the diarrhoea in a dog suffering from black tongue; since this date many people have treated human pellagrins with nicotinic acid. Results from this form of treatment have been sp successful that nicotinic acid is now established as a specific cure for pellagra. A large amount of research has been carried ?ut in the United States where pellagra is very common. Smith et al. (1937) reported a cure with 60 mg. of nicotinic acid daily for twelve days. The appetite improved after 24 hours and Rental improvement was noted after 48 hours. The skin was improved after 3 days. Spies et al. (1938) reported an immediate increase in appetite and cessation of nausea and diarrhoea. Twenty-four hours after administration of nicotinic acid, the tongue became less /sore and salivation diminished. He recommended a full well-balanced diet in addition to nicotinic acid.
منابع مشابه
Observations on the Use of Nicotinic Acid in the Treatment of Pellagra and Allied Conditions
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